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KMID : 0350519920450031053
Journal of Catholic Medical College
1992 Volume.45 No. 3 p.1053 ~ p.1066
Clinical and Histopathologic Study Korean Facial Pigmented Patches


Abstract
This study was aimed to evaluate the brownish pigmented facial patches of the Korean people clinically and histopathologically. One hundred and twenty biopsy specimens out of 118 patients were included and the histopathologic characteristics of
the
revised diagnoses were discribed and discussed.
@ES The results were summarised as follows:
@EN 1. The average age at visit was highest in benign lichenoid keratosis(BLK)(55.4 years old) and then seborrheic keratosis, reticulated type(SKR)(52.6 years old), lentigo senilis(LS)(50.3 years old), lentigo-like pigmented patch(LLPP)(44.2
years
old)
and large cell acanthoma(LCA)(42.5 years old) in decreasing orders.
2. The size of the lesion was smallest in SKR(6.5mm in diameter) and then BLK(8.9mm), LS(10.0mm), LLPP(13.2mm) and LCA(15.0mm) in increasing orders.
3. The incidence of the revised histopathologic diagnoses were LS(63 cases, 47.0%), BLK(28 cases, 20.9%), LLPP(26 cases, 19.4%), SKR(15 cases, 11.2%), and LCA(2 cases, 1.5%). Eleven cases of 63 LS(17.5%) were combined with SKR and 3 cases of
LS(4.8%)
were combined with BLK.
4. Only 16 cases of 63 LS(25.4%) showed marked elongation of rate ridges and the others showed slight(27 cases, 42.9%) or moderate(20 cases, 31.7%) elongation. But 60 cases(95.2%) showed club shaped change of rete ridges. In all 26 cases of
LLPP,
the
epidermis showed no elongation of ridges and no increase of melanocytes in the basal layer.
5. The diagnostic consistency rates between the revised diagnosis and the clinical diagnosis and between the revised diagnosis and the histopathologic diagnosis were highest in SKR(46.7%). In LS and LLPP consistency rates of the clinical
diagnoses
were
33.3% and 11.5%, respectively, The consistency rate of the histopathologic diagnosis in LS were 27.0% and none of the histopathologic diagnosis was consistent with revised diagnosis in LLPP. In BLK and LCA, none of the clinical and
histopathologic
diagnoses were consistent with revised diagnoses.
From these results it is considered that LS, BLK, SKR, and LCA are the diagnoses to the brownish pigmented facial patches of the Korean people which have not been diagnosed properly and definitely by the dermatologists and the pathologists. It is
conceived that this is because the clinical findings of the dieases are very similar and the histopathlogic findings of LS are somewhat different from those in the commonly cited literatures. Further study will be necessary to verify the
suggestion
that
BLK, LLPP, SKR and LCA share the same pathogenesis as LS and have the close relationship between them in their development and evolution.
KEYWORD
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